Destanni Mone Henderson (born February 2, 1999) is an American professional basketball player for the Indiana Fever of the Women's National Basketball Association (WNBA). Henderson played college basketball for the South Carolina Gamecocks. She played for Fort Myers Senior High School in her hometown of Fort Myers, Florida, where she won three straight state titles. Henderson was rated a five-star recruit and the number one point guard in the 2018 class by ESPN, as well as a McDonald's All-American. She became a full-time starter in her junior season at South Carolina, in which she helped lead the Gamecocks to the Final Four, and made the First Team All-SEC as a senior. Henderson competes for the United States national team and won a gold medal at the 2021 FIBA AmeriCup.